References

vestar

Вестник аритмологии

Journal of Arrhythmology

1561-86412658-7327

НАО «Инкарт»

10.35336/VA-1184

vestar-1241

Research Article

ОБЗОРЫ

REVIEWS

Семейная фибрилляция предсердий как полигенное заболевание со структурными аномалиями сердца: оценка генетического риска и возможности генной терапии

Familial atrial fibrillation as a polygenic disease with structural cardiac abnormalities: assessment of genetic risk and possibilities for gene therapy

https://orcid.org/0000-0003-3786-7559

Искендеров

Б. Г.

Iskenderov

B. G.

Бахрам Гусейнович Искендеров

Пенза, ул. Стасова, 8А

Bahram Iskenderov

Penza, 8A Stasov str.

iskenderovbg@mail.ru

Пензенский институт усовершенствования врачей - филиал ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» МЗ РФРоссияPenza Institute of Advanced Training of Doctors - branch of the Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian FederationRussian Federation

2023

18072023

303

e1-e10

2023

Искендеров Б.Г.

Iskenderov B.G.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://vestar.elpub.ru/jour/article/view/1241

Рассматривается распространенность семейной фибрилляции предсердий (ФП) в общей популяции и в структуре ФП, а также анализируются генетические предикторы ФП и патогенетические механизмы ремоделирования предсердий. Обсуждается оценка генетического риска возникновения ФП, прогнозирования ее исходов и эффективности терапии ФП, а также перспективы генной терапии ФП.

The prevalence of familial atrial fibrillation (AF) in the general population and in the structure of AF is considered, and genetic predictors of AF and pathogenetic mechanisms of atrial remodeling are analyzed. The assessment of the genetic risk of AF occurrence, the prediction of its outcomes and the effectiveness of AF therapy, as well as the prospects for AF gene therapy are discussed.

антиаритмическая терапиягенетическое тестированиекатетерная аблацияпредсердная кардиомиопатияфибрилляция предсердий

antiarrhythmic therapygenetic testingcatheter ablationatrial cardiomyopathyatrial fibrillation

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The authors declare that there are no conflicts of interest present.