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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestar</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник аритмологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Arrhythmology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-8641</issn><issn pub-type="epub">2658-7327</issn><publisher><publisher-name>НАО «Инкарт»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestar-376</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>БЕЗОПАСНОСТЬ ОДНОВРЕМЕННОГО ПРИМЕНЕНИЯ НЕПРЯМЫХ И ПРЯМЫХ АНТИКОАГУЛЯНТОВ ПРИ КАТЕРНОЙ АБЛАЦИИ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ: ИССЛЕДОВАНИЕ НА БОЛЬШОЙ ГРУППЕ ПАЦИЕНТОВ</article-title><trans-title-group xml:lang="en"><trans-title>SAFETY OF SIMULTANEOUS USE OF DIRECT AND INDIRECT ANTICOAGULANTS IN CATHETER ABLATION OF ATRIAL FIBRILLATION: STYUDY ON LARGE PATIENT GROUP</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>D. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гуреев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gureev</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свиридова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sviridova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миллер</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Miller</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриевская</surname><given-names>Н. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrievskaya</surname><given-names>N. O.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Оршанская</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Orshanskaya</surname><given-names>V. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маринин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Marinin</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГУ «Федеральный центр сердца, крови и эндокринологии им. В.А.Алмазова»</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГОУ ВПО «СПб ГМА им. И.И. Мечникова», Санкт-Петербург</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2020</year></pub-date><volume>53</volume><issue>53</issue><fpage>21</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайлов Е.Н., Лебедев Д.С., Гуреев С.В., Свиридова Н.В., Миллер Ю.В., Дмитриевская Н.О., Яковлева Е.И., Оршанская В.С., Маринин В.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Михайлов Е.Н., Лебедев Д.С., Гуреев С.В., Свиридова Н.В., Миллер Ю.В., Дмитриевская Н.О., Яковлева Е.И., Оршанская В.С., Маринин В.А.</copyright-holder><copyright-holder xml:lang="en">Mikhailov E.N., Lebedev D.S., Gureev S.V., Sviridova N.V., Miller Y.V., Dmitrievskaya N.O., Yakovleva E.I., Orshanskaya V.S., Marinin V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestar.elpub.ru/jour/article/view/376">https://vestar.elpub.ru/jour/article/view/376</self-uri><abstract><p>С целью ретроспективного анализа безопасности проведения катетерных вмешательств по поводу фибрилляции предсердий на фоне одновременного применения пероральных антикоагулянтов в терапевтической дозе и внутривенного введения нефракционированного гепарина проанализированы результаты лечения 310 пациентов (58%мужчин), средний возраст которых составил 53,9±10,5 (19-75) лет.</p></abstract><trans-abstract xml:lang="en"><p>To assess retrospectively the safety of catheter procedures for atrial fibrillation at the background of combined anticoagulant therapy, i.e. simultaneous use of both oral intake of anticoagulants in therapeutic doses and intravenous administration of non fractionated Heparin, the outcomes were studied in 310 patients aged 19-75 years.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>радиочастотная катетерная аблация</kwd><kwd>антикоагулянтная терапия</kwd><kwd>варфарин</kwd><kwd>нефракционированный гепарин</kwd><kwd>тромбоэмболические осложнения</kwd><kwd>кровотечения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>radiofrequency catheter ablation</kwd><kwd>anticoagulant treatment</kwd><kwd>Warfarin</kwd><kwd>non fractionated Heparin</kwd><kwd>thromboembolic events</kwd><kwd>bleeding</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Calkins H., Brugada J., Packer D.L. et al. 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