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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestar</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник аритмологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Arrhythmology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-8641</issn><issn pub-type="epub">2658-7327</issn><publisher><publisher-name>НАО «Инкарт»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestar-58</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>КАК ИЗМЕНИЛОСЬ ПРИМЕНЕНИЕ АНТИКОАГУЛЯНТОВ У ПАЦИЕНТОВ С НЕКЛАПАННОЙ ФИБРИЛЛЯЦИЕЙ ПРЕДСЕРДИЙ</article-title><trans-title-group xml:lang="en"><trans-title>TRENDS IN USE OF ANTICOAGULANTS IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рычков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Rychkov</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хорькова</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Khorkova</surname><given-names>N. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минулина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Minulina</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Тюменский кардиологический научный центр; Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>17</day><month>04</month><year>2019</year></pub-date><volume>0</volume><issue>87</issue><fpage>29</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рычков А.Ю., Хорькова Н.Ю., Минулина А.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Рычков А.Ю., Хорькова Н.Ю., Минулина А.В.</copyright-holder><copyright-holder xml:lang="en">Rychkov A.Y., Khorkova N.Y., Minulina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestar.elpub.ru/jour/article/view/58">https://vestar.elpub.ru/jour/article/view/58</self-uri><abstract><p>С целью сопоставления адекватности применения антикоагулянтов для профилактики ишемического инсульта и системных эмболий у пациентов с фибрилляцией предсердий неклапанной этиологии в реальной клинической практике в 2007-2008 и 2014 годах проведен анализ 1079 историй болезни.</p></abstract><trans-abstract xml:lang="en"><p>To compare adequacy of application of anticoagulants for prevention of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation in the real clinical practice in 2007 2008 and 2014, the analysis of 1079 medical charts was performed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>пероральные антикоагулянты</kwd><kwd>ишемический инсульт</kwd><kwd>международное нормализованное отношение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>oral anticoagulants</kwd><kwd>ischemic stroke</kwd><kwd>international normalized ratio</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Диагностика и лечение фибрилляции предсердий, рекомендации РКО, ВНОА и АССХ // Российский кардиологический журнал, 2014, № 4 (102), приложение 3.</mixed-citation><mixed-citation xml:lang="en">Диагностика и лечение фибрилляции предсердий, рекомендации РКО, ВНОА и АССХ // Российский кардиологический журнал, 2014, № 4 (102), приложение 3.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kirchhof P., Benussi S., Kotecha D., et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC Endorsed by the European Stroke Organisation (ESO) // Eur Heart J. 2016; doi: 10.1093/eurheartj/ehw210.</mixed-citation><mixed-citation xml:lang="en">Kirchhof P., Benussi S., Kotecha D., et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC Endorsed by the European Stroke Organisation (ESO) // Eur Heart J. 2016; doi: 10.1093/eurheartj/ehw210.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">CardioPulse Articles / Anticoagulants reduce risk of death in atrial fibrillation patients by 38% // Eur Heart J. 2016; 37: 860-867.</mixed-citation><mixed-citation xml:lang="en">CardioPulse Articles / Anticoagulants reduce risk of death in atrial fibrillation patients by 38% // Eur Heart J. 2016; 37: 860-867.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Camm A.J., Pinto F.J., Hankey G.J., et al. 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