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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vestar</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник аритмологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Arrhythmology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-8641</issn><issn pub-type="epub">2658-7327</issn><publisher><publisher-name>НАО «Инкарт»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vestar-84</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>НАРУШЕНИЯ ДЫХАНИЯ ВО СНЕ У БОЛЬНЫХ С ФИБРИЛЛЯЦИЕЙ ПРЕДСЕРДИЙ</article-title><trans-title-group xml:lang="en"><trans-title>SLEEP BREATHING DISORDERS IN PATIENTS WITH ATRIAL FIBRILLATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акобян</surname><given-names>С. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Akobyan</surname><given-names>S. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коростовцева</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korostovtseva</surname><given-names>L. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вареницына</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Varenitsyna</surname><given-names>S. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенов</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenov</surname><given-names>A. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочкарев</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bochkarev</surname><given-names>M. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свиряев</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sviryaev</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ «Северо-Западный федеральный медицинский исследовательский центр имени В.А.Алмазова» МЗ РФ</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ФГБУ «Северо-Западный федеральный медицинский исследовательский центр имени В.А.Алмазова» МЗ РФ; ФГБУН «Институт эволюционной физиологии и биохимии имени И.М. Сеченова» РАН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>17</day><month>04</month><year>2019</year></pub-date><volume>0</volume><issue>90</issue><fpage>39</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Акобян С.Г., Коростовцева Л.С., Вареницына С.Ю., Семенов А.П., Бочкарев М.В., Свиряев Ю.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Акобян С.Г., Коростовцева Л.С., Вареницына С.Ю., Семенов А.П., Бочкарев М.В., Свиряев Ю.В.</copyright-holder><copyright-holder xml:lang="en">Akobyan S.G., Korostovtseva L.S., Varenitsyna S.Y., Semenov A.P., Bochkarev M.V., Sviryaev Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vestar.elpub.ru/jour/article/view/84">https://vestar.elpub.ru/jour/article/view/84</self-uri><abstract><p>Приводятся данные о связи нарушения дыхания во время сна (преимущественно синдрома обструктивного апноэ во время сна) c фибрилляцией предсердий, о его влиянии на прогноз пациентов с данным типом аритмии.</p></abstract><trans-abstract xml:lang="en"><p>The data are given on the relationship between the sleep breathing disorders (predominantly, obstructive sleep apnea) with atrial fibrillation and their effect on the outcomes in subjects with the arrhythmia.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нарушения дыхания во время сна</kwd><kwd>синдром обструктивного апноэ сна</kwd><kwd>фибрилляция предсердий</kwd><kwd>артериальная гипертензия</kwd><kwd>ожирение</kwd><kwd>СРАР-терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sleep breathing disorders</kwd><kwd>obstructive sleep apnea</kwd><kwd>atrial fibrillation</kwd><kwd>arterial hypertension</kwd><kwd>obesity</kwd><kwd>CPAP therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Van Wagoner D.R., Piccini J.P., Albert C.M., Anderson M.E. Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013.</mixed-citation><mixed-citation xml:lang="en">Van Wagoner D.R., Piccini J.P., Albert C.M., Anderson M.E. Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Shao X.H., Yang Y.M., Zhu J., Zhang H. et al. Comparison of the clinical features and outcomes in two age-groups of elderly patients with atrial fibrillation. Clin Interv Aging. 2014; 9: 1335-1342. doi: 10.2147/CIA.S67123.</mixed-citation><mixed-citation xml:lang="en">Shao X.H., Yang Y.M., Zhu J., Zhang H. et al. Comparison of the clinical features and outcomes in two age-groups of elderly patients with atrial fibrillation. Clin Interv Aging. 2014; 9: 1335-1342. doi: 10.2147/CIA.S67123.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Wдndell P.E., Carlsson A.C., Sundquist J., Johansson S.E. Pharmacotherapy and mortality in atrial fibrillation-a cohort of men and women 75 years or older in Sweden. Age Ageing. 2015; 44(2): 232-238. doi: 10.1093/ageing/afu153.</mixed-citation><mixed-citation xml:lang="en">Wдndell P.E., Carlsson A.C., Sundquist J., Johansson S.E. Pharmacotherapy and mortality in atrial fibrillation-a cohort of men and women 75 years or older in Sweden. Age Ageing. 2015; 44(2): 232-238. doi: 10.1093/ageing/afu153.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Reiffel J.A. Atrial fibrillation and stroke: epidemiology. Am J Med. 2014; 127(4): e15-e16.</mixed-citation><mixed-citation xml:lang="en">Reiffel J.A. Atrial fibrillation and stroke: epidemiology. Am J Med. 2014; 127(4): e15-e16.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ревишвили А.Ш., Сулимов В.А. Фибрилляция и трепетание предсердий. Кардиология. Национальное руководство. 2015.</mixed-citation><mixed-citation xml:lang="en">Ревишвили А.Ш., Сулимов В.А. Фибрилляция и трепетание предсердий. Кардиология. Национальное руководство. 2015.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Peppard P.E., Young T., Barnet J.H., Palta M. Increased prevalence of sleep-disordered breathing in adults. Am. J. Epidemiol. 2013 May 1; 177 (9): 1006-14.</mixed-citation><mixed-citation xml:lang="en">Peppard P.E., Young T., Barnet J.H., Palta M. Increased prevalence of sleep-disordered breathing in adults. Am. J. Epidemiol. 2013 May 1; 177 (9): 1006-14.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Левин Я.И., Полуэктов М.Г. Расстроиства сна и их лечение // Consilium medicum. 2008. No 2. С. 137-142.</mixed-citation><mixed-citation xml:lang="en">Левин Я.И., Полуэктов М.Г. Расстроиства сна и их лечение // Consilium medicum. 2008. No 2. С. 137-142.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Michelena H., Powell B.D., Brady P.A., Friedman P.A. Gender in atrial fibrillation: Ten years later. Gend Med. 2010 Jun; 7(3): 206-17. doi: 10.1016/j.genm.2010.06.001.</mixed-citation><mixed-citation xml:lang="en">Michelena H., Powell B.D., Brady P.A., Friedman P.A. Gender in atrial fibrillation: Ten years later. Gend Med. 2010 Jun; 7(3): 206-17. doi: 10.1016/j.genm.2010.06.001.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lavie P. Who was the first to use the term Pickwickian in connection with sleepy patients? History of sleep apnoea syndrome. Sleep Med Rev. 2008; 12(1): 5-17.</mixed-citation><mixed-citation xml:lang="en">Lavie P. Who was the first to use the term Pickwickian in connection with sleepy patients? History of sleep apnoea syndrome. Sleep Med Rev. 2008; 12(1): 5-17.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bhattacharyya N., Blake S.P., Fried M.P. Assessment of the airway in obstructive sleep apnea syndrome with 3-dimensional airway computed tomography. Otolaryngology: head and neck surgery 2000; 123: 444-449.</mixed-citation><mixed-citation xml:lang="en">Bhattacharyya N., Blake S.P., Fried M.P. Assessment of the airway in obstructive sleep apnea syndrome with 3-dimensional airway computed tomography. Otolaryngology: head and neck surgery 2000; 123: 444-449.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Eckert D.J., Malhotra A. Pathophysiology of Adult Obstructive Sleep Apnea. Proceedings of the American thoracic society 2008; 5: 144-153.</mixed-citation><mixed-citation xml:lang="en">Eckert D.J., Malhotra A. Pathophysiology of Adult Obstructive Sleep Apnea. Proceedings of the American thoracic society 2008; 5: 144-153.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Rivlin J., Hoffstein V., Kalbfleisch J, McNicholas W. Upper airway morphology in patients with idiopathic obstructive sleep apnea. Am. Rev. Respir. Dis. 1984 Mar; 129 (3): 355-60.</mixed-citation><mixed-citation xml:lang="en">Rivlin J., Hoffstein V., Kalbfleisch J, McNicholas W. Upper airway morphology in patients with idiopathic obstructive sleep apnea. Am. Rev. Respir. Dis. 1984 Mar; 129 (3): 355-60.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gami A.S., Pressman G., Caples S.M., Kanagala R. Association of atrial fibrillation and obstructive sleep apnea. Circulation. 2004 Jul 27; 110(4): 364-7.</mixed-citation><mixed-citation xml:lang="en">Gami A.S., Pressman G., Caples S.M., Kanagala R. Association of atrial fibrillation and obstructive sleep apnea. Circulation. 2004 Jul 27; 110(4): 364-7.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Szymanski F.M., Platek A.E., Karpinski G. et al. Obstructive sleep apnea in patients with atrial fibrillation: prevalence, determinants and clinical characteristics of patients in Polish population. Kardiol Pol. 2014; 72: 716-24.</mixed-citation><mixed-citation xml:lang="en">Szymanski F.M., Platek A.E., Karpinski G. et al. Obstructive sleep apnea in patients with atrial fibrillation: prevalence, determinants and clinical characteristics of patients in Polish population. Kardiol Pol. 2014; 72: 716-24.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Mehra R., Benjamin E.J., Shahar E., Gottlieb D.J. Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study. Am. J. Respir. Crit. Care Med. 2006 Apr 15; 173 (8): 910-6.</mixed-citation><mixed-citation xml:lang="en">Mehra R., Benjamin E.J., Shahar E., Gottlieb D.J. Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study. Am. J. Respir. Crit. Care Med. 2006 Apr 15; 173 (8): 910-6.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Tanigawa T., Yamagishi K., Sakurai S., Muraki I. Arterial oxygen desaturation during sleep and atrial fibrillation. Heart. 2006 Dec; 92 (12): 1854-5.</mixed-citation><mixed-citation xml:lang="en">Tanigawa T., Yamagishi K., Sakurai S., Muraki I. Arterial oxygen desaturation during sleep and atrial fibrillation. Heart. 2006 Dec; 92 (12): 1854-5.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Foster G.E., Poulin M.J., Hanly P.J. Intermittent hypoxia and vascular function: implications for obstructive sleep apnoea. Exp Physiol. 2007; 92(1): 51-65.</mixed-citation><mixed-citation xml:lang="en">Foster G.E., Poulin M.J., Hanly P.J. Intermittent hypoxia and vascular function: implications for obstructive sleep apnoea. Exp Physiol. 2007; 92(1): 51-65.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Gami A.S., Hodge D.O., Herges R.M., et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation. Journal of the American College of Cardiology 2007; 49: 565- 571.</mixed-citation><mixed-citation xml:lang="en">Gami A.S., Hodge D.O., Herges R.M., et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation. Journal of the American College of Cardiology 2007; 49: 565- 571.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Вейн А.М. Синдром апноэ во сне и другие расстройства дыхания, связанные со сном: клиника, диагностика, лечение. М.: 2002; 310 с</mixed-citation><mixed-citation xml:lang="en">Вейн А.М. Синдром апноэ во сне и другие расстройства дыхания, связанные со сном: клиника, диагностика, лечение. М.: 2002; 310 с</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Mooe T., Gullsby S., Rabben T., Eriksson P. Sleep-disordered breathing: a novel predictor of atrial fibrillation after coronary artery bypass surgery. Coron Artery Dis. 1996 Jun; 7(6): 475-8.</mixed-citation><mixed-citation xml:lang="en">Mooe T., Gullsby S., Rabben T., Eriksson P. Sleep-disordered breathing: a novel predictor of atrial fibrillation after coronary artery bypass surgery. Coron Artery Dis. 1996 Jun; 7(6): 475-8.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Hendrikx T., Sundqvist M., Sandstrцm H., Sahlin C. Atrial fibrillation among patients under investigation for suspected obstructive sleep apnea. 2017 Feb DOI: 10.1371/journal.pone.0171575</mixed-citation><mixed-citation xml:lang="en">Hendrikx T., Sundqvist M., Sandstrцm H., Sahlin C. Atrial fibrillation among patients under investigation for suspected obstructive sleep apnea. 2017 Feb DOI: 10.1371/journal.pone.0171575</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Poli M., Philip P., Taillard J., Debruxelles S. Atrial fibrillation is a major cause of stroke in apneic patients: a prospective study. Sleep Med. 2017 Feb; 30: 251-254. doi: 10.1016/j.sleep.2015.07.031. Epub 2016 Mar 4.</mixed-citation><mixed-citation xml:lang="en">Poli M., Philip P., Taillard J., Debruxelles S. Atrial fibrillation is a major cause of stroke in apneic patients: a prospective study. Sleep Med. 2017 Feb; 30: 251-254. doi: 10.1016/j.sleep.2015.07.031. Epub 2016 Mar 4.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Szymanski F.M., Lip G.Y., Filipiak K.J., Platek A. Stroke Risk Factors Beyond the CHA2DS2-VASc Score: Can We Improve Our Identification of “High Stroke Risk” Patients With Atrial Fibrillation? 2015 Dec 1; 116(11): 1781-8. doi: 10.1016/j.amjcard.2015.08.049. Epub 2015 Sep 11.</mixed-citation><mixed-citation xml:lang="en">Szymanski F.M., Lip G.Y., Filipiak K.J., Platek A. Stroke Risk Factors Beyond the CHA2DS2-VASc Score: Can We Improve Our Identification of “High Stroke Risk” Patients With Atrial Fibrillation? 2015 Dec 1; 116(11): 1781-8. doi: 10.1016/j.amjcard.2015.08.049. Epub 2015 Sep 11.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ling Z., Yuemei H., Sunny S. P. Obstructive Sleep Ap-noea and Atrial Fibrillation</mixed-citation><mixed-citation xml:lang="en">Ling Z., Yuemei H., Sunny S. P. Obstructive Sleep Ap-noea and Atrial Fibrillation</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Rossi V.A., Kohler M. Effects of obstructive sleep apnoea on heart rhythm // Eur. Respir. J.2013. Vol.41.P.1439-1451</mixed-citation><mixed-citation xml:lang="en">Rossi V.A., Kohler M. Effects of obstructive sleep apnoea on heart rhythm // Eur. Respir. J.2013. Vol.41.P.1439-1451</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Narkiewicz K., Van de Borne P.J., Cooley R.L., Dyken M.E. Sympathetic activity in obese subjects with and without obstructive sleep apnea._Circulation. 1998 Aug 25; 98(8): 772-6.</mixed-citation><mixed-citation xml:lang="en">Narkiewicz K., Van de Borne P.J., Cooley R.L., Dyken M.E. Sympathetic activity in obese subjects with and without obstructive sleep apnea._Circulation. 1998 Aug 25; 98(8): 772-6.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Narkiewicz K., Van de Borne P.J., Montano N., Dyken M.E. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea._Circulation. 1998 Mar 17; 97(10): 943-5.</mixed-citation><mixed-citation xml:lang="en">Narkiewicz K., Van de Borne P.J., Montano N., Dyken M.E. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea._Circulation. 1998 Mar 17; 97(10): 943-5.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Osanai S., Akiba Y., Fujiuchi S., Nakano H. Depression of peripheral chemosensitivity by a dopaminergic mechanism in patients with obstructive sleep apnoea syndrome. Eur Respir J. 1999; 13(2): 418-423.</mixed-citation><mixed-citation xml:lang="en">Osanai S., Akiba Y., Fujiuchi S., Nakano H. Depression of peripheral chemosensitivity by a dopaminergic mechanism in patients with obstructive sleep apnoea syndrome. Eur Respir J. 1999; 13(2): 418-423.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Mahamed S., Hanly P.J., Gabor J., Beecroft J. Overnight changes of chemoreflex control in obstructive sleep apnoea patients. Respir Physiol Neurobiol. 2005; 146(2- 3): 279-90.</mixed-citation><mixed-citation xml:lang="en">Mahamed S., Hanly P.J., Gabor J., Beecroft J. Overnight changes of chemoreflex control in obstructive sleep apnoea patients. Respir Physiol Neurobiol. 2005; 146(2- 3): 279-90.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Foster G.E., Poulin M.J., Hanly P.J. Intermittent hypoxia and vascular function: implications for obstructive sleep apnoea. Exp Physiol. 2007; 92(1): 51-65.</mixed-citation><mixed-citation xml:lang="en">Foster G.E., Poulin M.J., Hanly P.J. Intermittent hypoxia and vascular function: implications for obstructive sleep apnoea. Exp Physiol. 2007; 92(1): 51-65.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Shamsuzzaman A.S., Gersh B.J., Somers V.K. Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA. 2003 Oct 8; 290(14): 1906-14.</mixed-citation><mixed-citation xml:lang="en">Shamsuzzaman A.S., Gersh B.J., Somers V.K. Obstructive sleep apnea: implications for cardiac and vascular disease. JAMA. 2003 Oct 8; 290(14): 1906-14.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Somers V.K., Dyken M.E., Skinner J.L. Autonomic and hemodynamic responses and interactions during the Mueller maneuver in humans // J. Auton. Nerv. Syst. 1993. Vol. 44. P. 2530-259.</mixed-citation><mixed-citation xml:lang="en">Somers V.K., Dyken M.E., Skinner J.L. Autonomic and hemodynamic responses and interactions during the Mueller maneuver in humans // J. Auton. Nerv. Syst. 1993. Vol. 44. P. 2530-259.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Linz D., Mahfoud F., Linz B., et al. Effect of obstructive respiratory events on blood pressure and renal perfusion in a pig model for sleep apnea, Am. J. Hypertens. 27 (2014) 1293-1300.</mixed-citation><mixed-citation xml:lang="en">Linz D., Mahfoud F., Linz B., et al. Effect of obstructive respiratory events on blood pressure and renal perfusion in a pig model for sleep apnea, Am. J. Hypertens. 27 (2014) 1293-1300.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Linz D., Hohl M., Nickel A., et al. Effect of renal denervation on neurohumoral acti- vation triggering atrial fibrillation in obstructive sleep apnea, Hypertension 62 (2013) 767-774.</mixed-citation><mixed-citation xml:lang="en">Linz D., Hohl M., Nickel A., et al. Effect of renal denervation on neurohumoral acti- vation triggering atrial fibrillation in obstructive sleep apnea, Hypertension 62 (2013) 767-774.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Mшller D.S., Lind P., Strunge B., Pedersen E.B. Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea, Am. J. Hypertens. 16 (2003) 274e80.</mixed-citation><mixed-citation xml:lang="en">Mшller D.S., Lind P., Strunge B., Pedersen E.B. Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea, Am. J. Hypertens. 16 (2003) 274e80.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Ramos P., Rubies C., Torres M., et al. Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells, Respir. Res. 15 (2014) 54.</mixed-citation><mixed-citation xml:lang="en">Ramos P., Rubies C., Torres M., et al. Atrial fibrosis in a chronic murine model of obstructive sleep apnea: mechanisms and prevention by mesenchymal stem cells, Respir. Res. 15 (2014) 54.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Ehrlich J.R., Hohnloser S.H., Nattel S. Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence, Eur. Heart J. 27 (2006) 512-518.</mixed-citation><mixed-citation xml:lang="en">Ehrlich J.R., Hohnloser S.H., Nattel S. Role of angiotensin system and effects of its inhibition in atrial fibrillation: clinical and experimental evidence, Eur. Heart J. 27 (2006) 512-518.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Li D., Shinagawa K., Pang L., et al. Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing induced congestive heart failure, Circulation 104 (2001) 2608-2614.</mixed-citation><mixed-citation xml:lang="en">Li D., Shinagawa K., Pang L., et al. Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing induced congestive heart failure, Circulation 104 (2001) 2608-2614.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Reil J.C., Hohl M., Selejan S., et al. Aldosterone promotes atrial fibrillation, Eur. Heart J. 33 (2012) 20982108.</mixed-citation><mixed-citation xml:lang="en">Reil J.C., Hohl M., Selejan S., et al. Aldosterone promotes atrial fibrillation, Eur. Heart J. 33 (2012) 20982108.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Tsai C.T., Chiang F.T., Tseng C.D., et al. Increased expression of mineralocorticoid re-ceptor in human atrial fibrillation and a cellular model of atrial fibrillation, J. Am. Coll. Cardiol. 55 (2010) 758-770.</mixed-citation><mixed-citation xml:lang="en">Tsai C.T., Chiang F.T., Tseng C.D., et al. Increased expression of mineralocorticoid re-ceptor in human atrial fibrillation and a cellular model of atrial fibrillation, J. Am. Coll. Cardiol. 55 (2010) 758-770.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Madrid A.H., Bueno M.G., Rebollo J.M., Marнn I. et al. Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: a prospective and randomized study. Circulation. 2002 Jul 16; 106(3): 331-6.</mixed-citation><mixed-citation xml:lang="en">Madrid A.H., Bueno M.G., Rebollo J.M., Marнn I. et al. Use of irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: a prospective and randomized study. Circulation. 2002 Jul 16; 106(3): 331-6.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Schmieder R.E., Kjeldsen S.E., Julius S., McInnes G.T. VALUE Trial Group. Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial. J Hypertens. 2008 Mar; 26(3): 403-11.</mixed-citation><mixed-citation xml:lang="en">Schmieder R.E., Kjeldsen S.E., Julius S., McInnes G.T. VALUE Trial Group. Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial. J Hypertens. 2008 Mar; 26(3): 403-11.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Бузунов Р.В., Ерошина В.А., Легейда И.В. Храп и синдром обструктивного апноэ сна: учебное пособие для врачеи. М., 2007.</mixed-citation><mixed-citation xml:lang="en">Бузунов Р.В., Ерошина В.А., Легейда И.В. Храп и синдром обструктивного апноэ сна: учебное пособие для врачеи. М., 2007.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Гончаров А.П., Волов Н.А., Шавдюк О.Ю., Таратухин Е.О. Синдром ночного апноэ как фактор риска сердечно-сосудистои патологии (обзор литературы) // Новые медицинские технологии. 2010. No 5.</mixed-citation><mixed-citation xml:lang="en">Гончаров А.П., Волов Н.А., Шавдюк О.Ю., Таратухин Е.О. Синдром ночного апноэ как фактор риска сердечно-сосудистои патологии (обзор литературы) // Новые медицинские технологии. 2010. No 5.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Сидоренко Б.А., Ерошина Е.В. Синдром обструктивного апноэ сна и нарушения ритма сердца // Кардиология. 2006. No 10. С. 44-50.</mixed-citation><mixed-citation xml:lang="en">Сидоренко Б.А., Ерошина Е.В. Синдром обструктивного апноэ сна и нарушения ритма сердца // Кардиология. 2006. No 10. С. 44-50.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Верткин А.Л., Максимова М.Ю., Любшина О.В. Нарушения сна у больных артериальной гипертензией и избыточной массой тела // Кардиоваскулярная терапия и профилактика. 2010. No 3. С. 10-19.</mixed-citation><mixed-citation xml:lang="en">Верткин А.Л., Максимова М.Ю., Любшина О.В. Нарушения сна у больных артериальной гипертензией и избыточной массой тела // Кардиоваскулярная терапия и профилактика. 2010. No 3. С. 10-19.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Parati G., Lombardi C., Hedner J., Bonsignore MR. Recommendations for the management of patients with obstructive sleep apnoea and hypertension. Eur Respir J. 2013 Mar; 41(3): 523-38. doi: 10.1183/09031936.00226711. Epub 2013 Feb 8.</mixed-citation><mixed-citation xml:lang="en">Parati G., Lombardi C., Hedner J., Bonsignore MR. Recommendations for the management of patients with obstructive sleep apnoea and hypertension. Eur Respir J. 2013 Mar; 41(3): 523-38. doi: 10.1183/09031936.00226711. Epub 2013 Feb 8.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Parati G., Lombardi C., Hedner J., Bonsignore MR. European Respiratory Society; EU COST ACTION B26 members. Position paper on the management of patients with obstructive sleep apnea and hypertension: joint recommendations by the European Society of Hypertension, by the European Respiratory Society and by the members of European COST (COoperation in Scientific and Technological research) ACTION B26 on obstructive sleep apnea. J Hypertens. 2012 Apr; 30(4): 633-46. doi: 10.1097/HJH.0b013e328350e53b.</mixed-citation><mixed-citation xml:lang="en">Parati G., Lombardi C., Hedner J., Bonsignore MR. European Respiratory Society; EU COST ACTION B26 members. Position paper on the management of patients with obstructive sleep apnea and hypertension: joint recommendations by the European Society of Hypertension, by the European Respiratory Society and by the members of European COST (COoperation in Scientific and Technological research) ACTION B26 on obstructive sleep apnea. J Hypertens. 2012 Apr; 30(4): 633-46. doi: 10.1097/HJH.0b013e328350e53b.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Bradley T.D., Hall M.J., Ando S.I., Floras J.S. Hemodynamic effects of simulated obstructive apneas in humans with and without heart failure, Chest 119 (2001) 1827 -1835.</mixed-citation><mixed-citation xml:lang="en">Bradley T.D., Hall M.J., Ando S.I., Floras J.S. Hemodynamic effects of simulated obstructive apneas in humans with and without heart failure, Chest 119 (2001) 1827 -1835.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Bradley T.D., Floras, J.S. Sleep apnea and heart failure, part I: obstructive sleep apnea, Circulation 107 (2003) 1671-1678.</mixed-citation><mixed-citation xml:lang="en">Bradley T.D., Floras, J.S. Sleep apnea and heart failure, part I: obstructive sleep apnea, Circulation 107 (2003) 1671-1678.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Orban M., Bruce C.J., Pressman G.S., et al., Dynamic changes of left ventricular performance and left atrial volume induced by the mueller maneuver in healthy young adults and implications for obstructive sleep apnea, atrial fibrillation, and heart failure, Am. J. Cardiol. 102 (2008) 1557-1561.</mixed-citation><mixed-citation xml:lang="en">Orban M., Bruce C.J., Pressman G.S., et al., Dynamic changes of left ventricular performance and left atrial volume induced by the mueller maneuver in healthy young adults and implications for obstructive sleep apnea, atrial fibrillation, and heart failure, Am. J. Cardiol. 102 (2008) 1557-1561.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Koshino Y., Villarraga H.R., Orban M., et al. Changes in left and right ventricular mechanics during the Mueller maneuver in healthy adults: a possible mechanism for abnormal cardiac function in patients with obstructive sleep apnea, Circulation 3 (2010) 282-289</mixed-citation><mixed-citation xml:lang="en">Koshino Y., Villarraga H.R., Orban M., et al. Changes in left and right ventricular mechanics during the Mueller maneuver in healthy adults: a possible mechanism for abnormal cardiac function in patients with obstructive sleep apnea, Circulation 3 (2010) 282-289</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Shivalkar B., Van de Heyning C., Kerremans M., Rinkevich D. Obstructive sleep apnea syndrome: more insights on structural and functional cardiac alterations, and the effects of treatment with continuous positive airway pressure. Am Coll Cardiol. 2006 Apr 4; 47(7): 1433-9.</mixed-citation><mixed-citation xml:lang="en">Shivalkar B., Van de Heyning C., Kerremans M., Rinkevich D. Obstructive sleep apnea syndrome: more insights on structural and functional cardiac alterations, and the effects of treatment with continuous positive airway pressure. Am Coll Cardiol. 2006 Apr 4; 47(7): 1433-9.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Fung J.W., Li T.S., Choy D.K., et al. Severe obstructive sleep apnea is associated with left ventricular diastolic dysfunction, Chest 121 (2002) 422-429. [55]</mixed-citation><mixed-citation xml:lang="en">Fung J.W., Li T.S., Choy D.K., et al. Severe obstructive sleep apnea is associated with left ventricular diastolic dysfunction, Chest 121 (2002) 422-429. [55]</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Pini, G. Tourkohoriti, Jordanoglou J. Left ventricular function in patients with obstructive sleep apnoea before and after treatment with nasal continuous positive airway pressure, Respiration 67 (2000) 1632-1666.</mixed-citation><mixed-citation xml:lang="en">Pini, G. Tourkohoriti, Jordanoglou J. Left ventricular function in patients with obstructive sleep apnoea before and after treatment with nasal continuous positive airway pressure, Respiration 67 (2000) 1632-1666.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Otto M.E., Belohlavek M., Romero-Corral A., Gami A.S. et all. Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apnea.</mixed-citation><mixed-citation xml:lang="en">Otto M.E., Belohlavek M., Romero-Corral A., Gami A.S. et all. Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apnea.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Colish J., Walker J.R., Elmayergi N., Almutairi S. Obstructive sleep apnea: effects of continuous positive airway pressure on cardiac remodeling as assessed by cardiac biomarkers, echocardiography, and cardiac MRI.</mixed-citation><mixed-citation xml:lang="en">Colish J., Walker J.R., Elmayergi N., Almutairi S. Obstructive sleep apnea: effects of continuous positive airway pressure on cardiac remodeling as assessed by cardiac biomarkers, echocardiography, and cardiac MRI.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Кушаковский М.С. Аритмии сердца. - Спб: Гиппократ, 1992. - 544 с.</mixed-citation><mixed-citation xml:lang="en">Кушаковский М.С. Аритмии сердца. - Спб: Гиппократ, 1992. - 544 с.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Shamsuzzaman A.S., Winnicki M., Lanfranchi P. et al., Elevated C-reactive protein in patients with obstructive sleep apnea, Circulation 105 (2002) 2462e4.</mixed-citation><mixed-citation xml:lang="en">Shamsuzzaman A.S., Winnicki M., Lanfranchi P. et al., Elevated C-reactive protein in patients with obstructive sleep apnea, Circulation 105 (2002) 2462e4.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Vgontzas A.N., Papanicolaou D.A., Bixler E.O., Kales A. Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity, J. Clin. Endocrinol. Metab. 82 (1997) 1313-1316.</mixed-citation><mixed-citation xml:lang="en">Vgontzas A.N., Papanicolaou D.A., Bixler E.O., Kales A. Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity, J. Clin. Endocrinol. Metab. 82 (1997) 1313-1316.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Zouaoui B.K., Van Meerhaeghe A., Doumit S., et al., Sleep apnoea- hypopnoea index is an independent predictor of high-sensitivity c-reactive protein elevation, Respiration 73 (2006) 243-246.</mixed-citation><mixed-citation xml:lang="en">Zouaoui B.K., Van Meerhaeghe A., Doumit S., et al., Sleep apnoea- hypopnoea index is an independent predictor of high-sensitivity c-reactive protein elevation, Respiration 73 (2006) 243-246.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Ohga E., Tomita T., Wada H., Yamamoto H. Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1, J. Appl. Physiol. 94 (2003) 179e84.</mixed-citation><mixed-citation xml:lang="en">Ohga E., Tomita T., Wada H., Yamamoto H. Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1, J. Appl. Physiol. 94 (2003) 179e84.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Wu N., Xu B., Xiang Y., et al. Association of inflammatory factors with occurrence and recurrence of atrial fibrillation: a meta-analysis, Int. J. Cardiol. 169 (2013) 62-72.</mixed-citation><mixed-citation xml:lang="en">Wu N., Xu B., Xiang Y., et al. Association of inflammatory factors with occurrence and recurrence of atrial fibrillation: a meta-analysis, Int. J. Cardiol. 169 (2013) 62-72.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Cai B.Z., Gong D.M., Liu Y., Pan Z.W. Homocysteine inhibits potassium channels in human atrial myocytes. Clin Exp Pharmacol Physiol. 2007 Sep; 34(9): 851-5.</mixed-citation><mixed-citation xml:lang="en">Cai B.Z., Gong D.M., Liu Y., Pan Z.W. Homocysteine inhibits potassium channels in human atrial myocytes. Clin Exp Pharmacol Physiol. 2007 Sep; 34(9): 851-5.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Marcucci R., Betti I., Cecchi E., Poli D. Hyperhomo-cysteinemia and vitamin B6 deficiency: new risk markers for nonvalvular atrial fibrillation? Am Heart J. 2004 Sep; 148(3): 456-61.</mixed-citation><mixed-citation xml:lang="en">Marcucci R., Betti I., Cecchi E., Poli D. Hyperhomo-cysteinemia and vitamin B6 deficiency: new risk markers for nonvalvular atrial fibrillation? Am Heart J. 2004 Sep; 148(3): 456-61.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Can M., Aзikgцz S., Mungan G., Bayraktaroрlu T. Serum cardiovascular risk factors in obstructive sleep apnea. Chest. 2006 Feb; 129(2): 233-7.</mixed-citation><mixed-citation xml:lang="en">Can M., Aзikgцz S., Mungan G., Bayraktaroрlu T. Serum cardiovascular risk factors in obstructive sleep apnea. Chest. 2006 Feb; 129(2): 233-7.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Lavie L., Perelman A., Lavie P. Plasma homocysteine levels in obstructive sleep apnea: association with cardiovascular morbidity. Chest. 2001 Sep; 120(3): 900-8.</mixed-citation><mixed-citation xml:lang="en">Lavie L., Perelman A., Lavie P. Plasma homocysteine levels in obstructive sleep apnea: association with cardiovascular morbidity. Chest. 2001 Sep; 120(3): 900-8.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Rubinsztajn R., Kumor M., Byskiniewicz K., Chazan R. The influence of 3 weeks therapy with continuous positive airway pressure on serum leptin and homocysteine concentration in patients with obstructive sleep apnea syndrome. Pneumonol Alergol Pol. 2006; 74(1): 63-7.</mixed-citation><mixed-citation xml:lang="en">Rubinsztajn R., Kumor M., Byskiniewicz K., Chazan R. The influence of 3 weeks therapy with continuous positive airway pressure on serum leptin and homocysteine concentration in patients with obstructive sleep apnea syndrome. Pneumonol Alergol Pol. 2006; 74(1): 63-7.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Svatikova A., Wolk R., Magera M.J., Shamsuzzaman A.S. Plasma homocysteine in obstructive sleep apnoea. Eur Heart J. 2004 Aug; 25(15): 1325-9.</mixed-citation><mixed-citation xml:lang="en">Svatikova A., Wolk R., Magera M.J., Shamsuzzaman A.S. Plasma homocysteine in obstructive sleep apnoea. Eur Heart J. 2004 Aug; 25(15): 1325-9.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Eckert D.J., Jordan A.S., Merchia P., Malhotra A. Central sleep apnea: Pathophysiology and treatment. Chest. 2007 Feb; 131 (2): 595-607.</mixed-citation><mixed-citation xml:lang="en">Eckert D.J., Jordan A.S., Merchia P., Malhotra A. Central sleep apnea: Pathophysiology and treatment. Chest. 2007 Feb; 131 (2): 595-607.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Sin D.D., Fitzgerald F., Parker J.D., Newton G. Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failure. Am. J. Respir. Crit. Care Med. 1999 Oct; 160 (4): 1101-6.</mixed-citation><mixed-citation xml:lang="en">Sin D.D., Fitzgerald F., Parker J.D., Newton G. Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failure. Am. J. Respir. Crit. Care Med. 1999 Oct; 160 (4): 1101-6.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Leung R.S., Huber M.A., Rogge T., Maimon N. Association between atrial fibrillation and central sleep apnea.</mixed-citation><mixed-citation xml:lang="en">Leung R.S., Huber M.A., Rogge T., Maimon N. Association between atrial fibrillation and central sleep apnea.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Grimm W., Sass J., Cassel W., Hildebrandt O. Severe central sleep apnea is associated with atrial fibrillation in patients with left ventricular systolic dysfunction. DOI: 10.1111/pace.12495</mixed-citation><mixed-citation xml:lang="en">Grimm W., Sass J., Cassel W., Hildebrandt O. Severe central sleep apnea is associated with atrial fibrillation in patients with left ventricular systolic dysfunction. DOI: 10.1111/pace.12495</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Friberg L., Hammar N., Rosenqvist M. Stroke in paroxysmal atrial fibrillation: report from the Stockholm Cohort of Atrial Fibrillation.</mixed-citation><mixed-citation xml:lang="en">Friberg L., Hammar N., Rosenqvist M. Stroke in paroxysmal atrial fibrillation: report from the Stockholm Cohort of Atrial Fibrillation.</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Watson T., Shantsila E., Lip GY. Mechanisms of thrombogenesis in atrial fibrillation: Virchow’s triad revisited.</mixed-citation><mixed-citation xml:lang="en">Watson T., Shantsila E., Lip GY. Mechanisms of thrombogenesis in atrial fibrillation: Virchow’s triad revisited.</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Oliver, K.M. Hypoxia activates NF-kB-dependent gene expression through the canonical signaling pathway / K.M. Oliver, J.F. Garvey, C.T. Ng [et al.] // Antioxid Redox Signal. - 2009. - Vol. 11. - P. 2057-2064.</mixed-citation><mixed-citation xml:lang="en">Oliver, K.M. Hypoxia activates NF-kB-dependent gene expression through the canonical signaling pathway / K.M. Oliver, J.F. Garvey, C.T. Ng [et al.] // Antioxid Redox Signal. - 2009. - Vol. 11. - P. 2057-2064.</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Hui D.S., Ko F.W., Fok J.P. (2004) The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome. Chest 125: 17681775. DOI 10.1378/chest.09-1778</mixed-citation><mixed-citation xml:lang="en">Hui D.S., Ko F.W., Fok J.P. (2004) The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome. Chest 125: 17681775. DOI 10.1378/chest.09-1778</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Szymanski F.M., Filipiak K.J., Platek A.E., Hrynkiewicz-Szymanska A. Assessment of CHADS2 and CHA 2DS 2-VASc scores in obstructive sleep apnea patients with atrial fibrillation, Sleep Breath. 19 (2015) 531-537.</mixed-citation><mixed-citation xml:lang="en">Szymanski F.M., Filipiak K.J., Platek A.E., Hrynkiewicz-Szymanska A. Assessment of CHADS2 and CHA 2DS 2-VASc scores in obstructive sleep apnea patients with atrial fibrillation, Sleep Breath. 19 (2015) 531-537.</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Yaranov D.M., Smyrlis A., Usatii N., et al., Effect of obstructive sleep apnea on frequency of stroke in patients with atrial fibrillation, Am. J. Cardiol. 115 (2015) 461 -465.</mixed-citation><mixed-citation xml:lang="en">Yaranov D.M., Smyrlis A., Usatii N., et al., Effect of obstructive sleep apnea on frequency of stroke in patients with atrial fibrillation, Am. J. Cardiol. 115 (2015) 461 -465.</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Platek A.E., Szymanski F.M., Filipiak K.J., Kotkowski M. Which components of the CHA2DS2-VASc score are the most important in ob- structive sleep apnea patients with atrial fibrillation? Blood Coagul. Fibrinolysis 27 (2016) 347-351.</mixed-citation><mixed-citation xml:lang="en">Platek A.E., Szymanski F.M., Filipiak K.J., Kotkowski M. Which components of the CHA2DS2-VASc score are the most important in ob- structive sleep apnea patients with atrial fibrillation? Blood Coagul. Fibrinolysis 27 (2016) 347-351.</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Szymanski F.M., Lip G.Y., Filipiak K.J., Platek A.E. Stroke risk factors beyond the CHA2DS2-VASc score: can we improve our identification of “high stroke risk” patients with atrial fibrillation? Am. J. Cardiol. 116 (2015) 1781-1788.</mixed-citation><mixed-citation xml:lang="en">Szymanski F.M., Lip G.Y., Filipiak K.J., Platek A.E. Stroke risk factors beyond the CHA2DS2-VASc score: can we improve our identification of “high stroke risk” patients with atrial fibrillation? Am. J. Cardiol. 116 (2015) 1781-1788.</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Kanagala R., Murali N.S., Friedman P.A., Ammash N. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation. 2003 May 27; 107 (20): 2589-94.</mixed-citation><mixed-citation xml:lang="en">Kanagala R., Murali N.S., Friedman P.A., Ammash N. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation. 2003 May 27; 107 (20): 2589-94.</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Patricia T. Atrial Fibrillation And Sleep Apnea: Considerations For A Dual Epidemic</mixed-citation><mixed-citation xml:lang="en">Patricia T. Atrial Fibrillation And Sleep Apnea: Considerations For A Dual Epidemic</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Holmqvist F., Guan N., Zhu Z., Kowey P.R., et all. Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation-Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). Am. Heart J. 2015 May; 169 (5): 647-654.e2.</mixed-citation><mixed-citation xml:lang="en">Holmqvist F., Guan N., Zhu Z., Kowey P.R., et all. Impact of obstructive sleep apnea and continuous positive airway pressure therapy on outcomes in patients with atrial fibrillation-Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF). Am. Heart J. 2015 May; 169 (5): 647-654.e2.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
