Mechanisms of atrial fibrillation in COVID-19
https://doi.org/10.35336/VA-2023-1-11
Abstract
Atrial fibrillation (AF) is the most frequent form of cardiac arrhythmia in COVID-19 infected patients. The occurrence of AF paroxysms is often associated with the acute period of infection in time. At the same time, the pathophysiological mechanisms of the occurrence of AF associated with COVID-19 remain insufficiently studied. The review considers the available literature data on the influence of factors such as reduced availability of angiotensin-converting enzyme 2 re- ceptors, interaction of the virus with the cluster of differentiation 147 and sialic acid, increased inflammatory signaling, “cytokine storm”, direct viral damage to the endothelium, electrolyte and acid-alkaline balance in the acute phase of severe illness and increased sympathetic activity.
About the Authors
K. A. Moseichuk
Ryazan State Medical University
Russian Federation
Russian Federation
Ryazan, 9 Visokovoltnaya str.
E. V. Filippov
Ryazan State Medical University
Russian Federation
Russian Federation
Ryazan, 9 Visokovoltnaya str.
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Review
For citations:
Moseichuk K.A., Filippov E.V. Mechanisms of atrial fibrillation in COVID-19. Journal of Arrhythmology. 2023;30(1):е6-е11. https://doi.org/10.35336/VA-2023-1-11
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