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COGNITIVE FUNCTIONS IN PATIENTS WITH PAROXYSMAL AND PERMANENT ATRIAL FIBRILLATION BEFORE AND AT DIFFERENT STAGES AFTER PERMANENT PACEMAKER IMPLANTATION

Abstract

To assess cognitive functions in patients with paroxysmal and permanent atrial fibrillation and the effect of permanent pacemaker implantation on them, 23 patients aged 62.8±5.5 years (men: 65.2%) were examined. To assess cognitive functions in patients with paroxysmal and permanent atrial fibrillation (AF) before and at different stages after implantation of permanent pacemaker, 23 patients with coronary heart disease aged 62.8±5.5 years (15 men [65.2%] and 8 women [34.8%]) were examined. The patients were distributed into two following groups: Group I (n=12; 52.2%) with permanent AF and Group II (n=11; 47.8%) with paroxysmal AF. The Status PF complex was used for assessment of cognitive functions. The parameters of visual and aural memory, attentional capacity, ideation using simple and complex analogies, simple hand-eye responses, as well as personal and state anxiety were assessed. The tests were performing before the pacemaker implantation as well as 5-7 days and 30-40 days following the pacemaker implantation. The comparative assessment of cognitive functions showed that both permanent and paroxysmal AF contributed to development of cognitive deficiency which was more pronounced in the patients with permanent AF. At the early stage after pacemaker implantation (Day 5 7), selected cognitive function parameters improved, primarily in the patients with paroxysmal AF. At the late stage after pacemaker implantation (Day 30 40), cognitive functions remained unchanged in the patients with paroxysmal AF and decreased in the patients with permanent AF. An insufficient improvement of cognitive functions in both groups could be caused by different reasons, including the negative impact of personal and state anxiety due to adaptation of a patient to pacemaker.

About the Authors

S. A. Skopetskaya
ГБОУ ВПО «Дальневосточный ГМУ» МЗ РФ; ФГБУ «Федеральный центр сердечно-сосудистой хирургии» МЗ РФ
Russian Federation


I. M. Davidovich
ГБОУ ВПО «Дальневосточный ГМУ» МЗ РФ
Russian Federation


T. E. Neapolitanskaya
ФГБУ «Федеральный центр сердечно-сосудистой хирургии» МЗ РФ
Russian Federation


References

1. Miyasaka Y., Barnes M.E., Gersh B.J. et al. Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence // Circulation. - 2006. - Vol. -114. - P.119-125;

2. Udompanich S., Lip G.Y., Apostolakis S. et al. Atrial fibrillation as a risk factor for cognitive impairment: a semi-systematic review // Q J Med. - 2013. - Vol. - 106. - P. 795-802

3. Клинические рекомендации по проведению электрофизиологических исследований, катетерной абляции и применению имплантируемых антиаритмических устройств. М. - 2013

4. Ефимова Н.Ю., Чернов В.И., Ефимова И.Ю. и др. Влияние имплантации электрокардиостимулятора на когнитивную дисфункцию у пациентов с постоянной формой фибрилляции предсердий: взаимосвязь с церебральной перфузией // Вестник аритмологии. - 2008. -№ 54. - C.15-19.

5. Gribbin G.M., Gallagher P., Young A.H. et al. The effect of pacemaker mode on cognitive function // Heart. -2005. - Vol. 91. - P. 1209-1210

6. Иванов В.И., Литвинова Н.А., Березина М.Г. Автоматизированный комплекс для индивидуальной оценки индивидуально-типологических свойств и функционального состояния организма человека «СТАТУС ПФ»//Валеология. - 2004. - № 4. - С. 70-73

7. Тарасова И.В., Трубникова О.А., Кухарева И.Н. Методические подходы к диагностике послеоперационной когнитивной дисфункции в кардиохирургической клинике // Комплексные проблемы сердечно-сосудистых заболеваний. - 2015. - № 4. - С. 73-78.

8. Marinigh R., Lip G.Y.H., Fiotti N. et al. Age as a risk factor for stroke in atrial fibrillation patients implications for thromboprophylaxis: Implications for thromboprophy-laxis//J Am Coll Cardiol. - 2010. - Vol. 56. - P. 827-837.

9. Деревнина Е.С., Акимова Н.С., Мартынович Т.В. и соавт. Когнитивные нарушения при фибрилляции предсердий на фоне сердечно-сосудистых заболеваний // Анналы аритмологии. - 2013. Т. 10. - № 2. - С. 87-94

10. Lip G.Y.H. Stroke in atrial fibrillation: epidemiology and thromboprophylaxis// J Thromb Haemost.- 2011.-Vol.9(Suppl. 1).-P.344-51.

11. Thacker E.L., McKnight B., Psaty B.M. et al. Atrial fibrillation and cognitive decline. A longitudinal cohort study // Neurology. - 2013. - Vol. 81. - P. 119-125.

12. Manolis A.S. Atrial Fibrillation and Cognitive Impair-ment//Hospital Chronicles.- 2015.-Vol.10(3).-P. 129-136.

13. Lin T., Wissner E., Tilz R. et al. Preserving Cognitive Function in Patients with Atrial Fibrillation // JAFIB. -2014. - Vol. 7(1). - P. 107-113.

14. Mavaddat N., Roalfe A., Fletcher K. et al. Warfarin Versus Aspirin for Prevention of Cognitive Decline in Atrial Fibrillation Randomized Controlled Trial (Birmingham Atrial Fibrillation Treatment of the Aged Study) // Stroke. -2014. - Vol. 45. - P. 1381-1386.

15. Jacobs V., Woller S.C., Stevens S. et al. Time outside of therapeutic range in atrial fibrillation patients is associated with long-term risk of dementia // Heart Rhythm. - 2014. -Vol. 11. - P. 2206-2213.

16. Kalantarian S., Ay H., Gollub RL. et al. Association between atrial fibrillation and silent cerebral infarctions: a systematic review and meta-analysis // Ann Intern Med. -2014. - Vol. 161. - P. 650-658.

17. Kakkar A.K., Mueller I., Bassand J.-P. et al. Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation at Risk of Stroke: Perspectives from the International, Observational, Prospective GARFIELD Registry // PLoS ONE. - 2013. - Vol. 8 (5). -P.63479.

18. Давидович И.М., Скопецкая С.А. Состояние памяти, внимания, уровня депрессии и тревожности у пациентов с ишемической болезнью сердца и постоянной электрокардиостимуляцией//Дальневосточный медицинский журнал. - 2015. - № 4. - С. 6-11.

19. Gaita F., Corsinovi L., Anselmino M. et al. Prevalence of silent cerebral ischemia in paroxysmal and persistent atrial fibrillation and correlation with cognitive function// J Am Coll Cardiol. - 2013. - Vol. 62. - P. 1990-1997.

20. Ganesan A.N., Chew D.P., Hartshorne T. et al. The impact of atrial fibrillation type on the risk of thromboembolism, mortality, and bleeding: a systematic review and meta-analysis // Eur Heart J. - 2016. - Vol. 37(20). - P. 1591-602.

21. Efimova I., Efimova N., Chernov V et al. Ablation and pacing: improving brain perfusion and cognitive function in patients with atrial fibrillation and uncontrolled ventricular rates//Pacing Clin Electrophysiol. - 2012.-Vol.35(3). -P. 320-6.

22. Сычёв О.С., Бородай А.А., Федькив С.В. и др. Качество жизни, тревога, депрессия и когнитивная дисфункция у больных с фибрилляцией предсердий неклапанного происхождения и немыми инфарктами головного мозга//Український кардіологічний журнал. -2015. - № 1. -.C. 54-64.


Review

For citations:


Skopetskaya S.A., Davidovich I.M., Neapolitanskaya T.E. COGNITIVE FUNCTIONS IN PATIENTS WITH PAROXYSMAL AND PERMANENT ATRIAL FIBRILLATION BEFORE AND AT DIFFERENT STAGES AFTER PERMANENT PACEMAKER IMPLANTATION. Journal of Arrhythmology. 2016;(85):34-39. (In Russ.)

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ISSN 1561-8641 (Print)
ISSN 2658-7327 (Online)