ВНЕЗАПНАЯ СЕРДЕЧНАЯ СМЕРТЬ МОЛОДЫХ ЛЮДЕЙ

С целью определения причин внезапной сердечной смерти проведен анализ аутопсий, протоколов вскрытий, протоколов участковых полицейских, анкетированный опрос родственников и/или свидетелей события, выполнены органометрия сердца, гистологическое, морфометрическое, иммунногистохимическое исследования миокарда желудочков, клапанов сердца, коронарных артерий у 128 молодых людей в возрасте от 14 до 35 лет.

внезапная сердечная смерть, генетически детерминированные заболевания сердца, аритмогенная дисплазия/кардиомиопатия правого желудочка, алкогольная кардиомиопатия, гипертрофическая кардиомиопатия, дилятационная кардиомиопатия, аутопсия-отрицательная смерть, миокардит, желудочковые аритмии, алкоголь, наркотики

1. Митрофанова Л.Б., Аминева Х.К. Пособие для врачей под редакцией проф. Г.Б.Ковальского «Макроскопический и органометрический анализ сердца в патологии» Городское патологоанатомическое бюро. СПб, 1998, 58 с.

2. Ahmad F. The molecular genetics of arrhythmogenic right ventricular dysplasia-cardiomyopathy // Clin. Invest. Med.-2003; 26: 167-178.

3. Albert C.M., Chae C.U., Grodstein F. et al. Prospective study of sudden cardiac death among women in the United States // Circulation. - 2003. - Vol. 107. - P. 2096-2101

4. Basso C., Thiene G., Corrado D. et al. Arrhythmogenic right ventricular cardiomyopathy: dysplasia, dystrophy or myocarditis? // Circulation 1996; 94: 985.

5. Basso C., Pilichou K., Carturan E. et al. Pathobiology of Arrhythmogenic Cardiomyopathy // Card Electrophysiol 2011;Clin 3:193-204

6. Becker L., Smith D., Rhodes K. Incidence of cardiac arrest: a neglected factor in evaluating survival rates // Ann Emerg Med 1993; 22: 86-91.

7. Cairns J.A., Connolly S.J., Roberts R., Gent M. Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIT // Lancet 1997; 349: 675-682.

8. Corrado D., Basso C., Rizzoli G. et al. Does sports activity enhance the risk of sudden death in adolescents and young adults? // J AmCollCardiol 2003; 42: 1959-1963.

9. Corrado D., Basso C., Schiavon M. et al. Screening for hypertrophic cardiomyopathyin young athletes // N Engl J Med 1998; 339: 364-9.

10. Corrado D., Thiene G., Nava A. et al. Exercize-related sudden death in the young. (abstract) // Eur. Heart J. - 1993. - Vol. 86. - P. 368A.

11. Doolan A., Langlois N., Semsarian C. Causes of sudden cardiac death in young Australians // MJA 2004; 180: 110-112.

12. Driscoll D.J., Edwards W.D. Sudden unexpected death in children and adolescents //J Am Col lCardiol 1985; 5: 118B-121B.

13. Drory Y., Turetz Y., Hiss Y. et al. Sudden unexpected death in persons less than 40 years of age // Am J Cardiol 1991; 68: 1388-92.

14. Eckart R., Scoville S., Shry E. et al. Causes of Sudden Death in Young Female Military Recruits // The American Journal of Cardiology 2006; 97: 1756-1758.

15. Eckart R., Scoville S., Campbell C. et al. Sudden death in young adults: a 25-year review of autopsies in military recruits //Ann Intern Med. 2004; 141: 829-834.

16. Einarsson G., Bjornsson J., Gunnarsson G. Sudden cardiac death in the young: a 30 year nationwide study in Iceland // Eur H Journal 2007; 26: (Abstract): 727.

17. Elliott P.M., Poloniecki J., Dickie S. et al. Sudden death in hypertrophic cardiomyopathy: identification of high risk patients // J Am CollCardiol 2000; 36: 2212-8.

18. Gottlieb S.S. Dead is dead - artificial definitions are no substitute // Lancet 1997; 349: 662-663.

19. Greene H.L., Richardson D.W., Barker A.H. Classification of deaths after myocardial infarction as arrhythmic or nonarrhythmic (The Cardiac Arrhythmia Pilot Study) // Am J Cardiol 1989; 63: 1-6.

20. Hinkle L.E., Thaler T. Clinical classification of cardiac deaths // Circulation 1982; 65: 457-464.

21. Huikuri H.V., Castellanos A., Myerburg R.J. Sudden death due to cardiac arrhythmias // N. Engl. J. Med. 2001. - Vol. 345. - P. 1473-1482.

22. Julian D.G, Camm A.J, Frangin G. et al. Randomised trial of effect of amiodarone on mortality in patients with lef ventricular dysfunction after recent myocardial infarction: EMIAT // Lancet 1997; 349: 667-674.

23. Karatolios K., Pankuweit S., Kisselbach C., Maisch B. Inflammatory cardiomyopathy // Hellenic J Cardiol. 2006. - Vol.47. - P. 54-65.

24. Marcus F.I., McKenna W.J., Sherrill D. et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia. Proposed Modification of the Task Force Criteria // European Heart J. - 2010. - Vol.31. - P. 806-814.

25. Maron B.J, Carney K.P, Lever H.M. et al. Relationship of race to sudden cardiac death in competitive athletes with hypertrophic cardiomyopathy // J Am Coll Cardiol 2003; 41: 974-80.

26. Messner T., Lundberg V Trends in sudden cardiac death in the northern Sweden MONICA area 1985-99 // J Intern Med. 2003; 253 (3): 320-8.

27. Molander N. Sudden natural death in later childhood and adolescence // Archives of Disease in Childhood 1982; 57: 572-576.

28. Morentin B., Suarez-Mier M., Audicana C. et al. Incidencia y causas de muertesubitaen menores de 36 anos // MedClin (Barc) 2001; 116: 281-285.

29. MorrisV.B., KeelanT., LeenE. et al. Sudden cardiac death in the young: a 1-year post-mortem analysis in the Republic of Ireland // Ir J Med Sci 2009; doi:10.1007./ s11845-009-0294-8.

30. MyerburgR.J, KesslerK.M, CastellanosA. Sudden cardiac death. Structure, function, and time-dependence of risk // Circulation 1992; 85 (Suppl I): I-2-1-10.

31. Norris R.M. Amiodarone after myocardial infarction: EMIAT and CAMIAT trials // Lancet 1997; 349: 1767-1770.

32. Pratt C.M., Greenway P.S., Schoenfeld M.H. Exploration of the precision of classifying sudden cardiac death // Circulation 1996; 93: 519-524.

33. PuranikR., ChowC.R., DuflouJ.A. et al. Sudden death in the young. // Heart Rhythm. -2005. - Vol. 2, N 12. - P. 1277-1282.

34. Rapaport E. Nomenclature and criteria for diagnosis of ischemic heart disease // Circulation 1979;59: 607-609.

35. Shen W.K., Edwards W., Hammill S. Sudden unexpected nontraumatic death in 54 young adults: A 30-year population-based study // Am J Cardiol 1995; 76: 148-152.

36. Straus S., Bleumink G., Dieleman J. et al. The incidence of sudden cardiac death in the general population // Journal of Clinical Epidemiology 2004; 57: 98-102.

37. Tester D.J., Ackerman M.J. The role of molecular autopsy in unexplained sudden cardiac death // Curr. Opin. Cardiol. - 2006. - Vol. 21. - P. 166-172.

38. TesterD.J., Spoon D.B., Valdivia H.H. et al. Targeted mutation alanalysis of the RyR2-encoded cardiac ryanodine receptor in sudden unexplained death: a molecular autopsy of 49 medical examiner/coroner’s cases // Mayo Clin. Proc. - 2004. - Vol. 79. - P. 1380-1384.

39. Thiene G., Nava A., Corrado D. et al. Right ventricular cardiomyopathy and sudden death in young people // N. Engl. J. Med. - 1988. - Vol. 318. - P. 129-133.

40. Turakhia M., Tseng Z.H. Sudden Cardiac death: Epidemiology, mechanisms and therapy // Curr. Probl. Cardiol. - 2007. - Vol. 32. - P. 501-546.

41. VanCamp S.P, Bloor C.M, Mueller F. et al. Nontraumatic sports death in high school and college athletes // MedSciSportsExerc 1995; 27: 641-647.

42. Virmani R., Burke A.R., Farb A. Pathologic experience in USA. In Nava A., Rossi L., editors: Arrhythmogenic right ventricular cardiomyopathy/dysplasia. Elsevier, Amsterdam, 1997. - P.87-93.

43. Vreede-Swagemakers J.J., Gorgels A.P., Dubois-Arbouw W.I. Out-of-hospital cardiac arrest in the 1990s: a population-based study in the Maastricht area on incidence, characteristics and survival // J. Am. Coll. Cardiol. - 1997. - Vol. 30. - P. 1500-1505.

44. Wisten A., Forsberg H., Krantz P., Messner T. Sudden cardiac death in 15-35 year olds in Sweden 1992-1999 // J Int Med 2002; 252: 529-536.

45. Wisten A. Sudden cardic death among the young in Sweden 1992-1999. From epidemiology to support of the bereaved. Umea, Sweden: Umea University; 2005.

46. Zipez D., Wellens H. Sudden Cardic Death // Circulation. - 1998.- Vol.98.-P.2334-2351.