МЕХАНИЧЕСКАЯ ДИССИНХРОНИЯ КАК ПРЕДИКТОР СУПЕРОТВЕТА НА СЕРДЕЧНУЮ РЕСИНХРОНИЗИРУЮЩУЮ ТЕРАПИЮ

С целью выявления клинических и морфофункциональных особенностей больных с хронической сердечной недостаточностью и суперответом на сердечную ресинхронизирующую терапию обследованы 79 пациентов (88,9% мужчин, средний возраст 53,7±9,1 года).

хроническая сердечная недостаточность, дисфункция левого желудочка, блокада левой ножки пучка Гиса, сердечная ресинхронизирующая терапия, суперответ, эхокардиография, тест шестиминутной ходьбы

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3. Cvijic M., Zizek D., Antolic B., Zupan I. Time Course of Electrical Remodelling of Native Conduction after Cardiac Resynchronization Therapy and Its Impact on Clinical Outcome. Journal of cardiac failure. 2016; doi: 10.1016/j.cardfail.2016.10.014.

4. van der Bijl P., Khidir M., Leung M. et al. Impact of QRS complex duration and morphology on left ventricular reverse remodelling and left ventricular function improvement after cardiac resynchronization therapy. European Journal of Heart Failure. 2017; doi: 10.1002/ejhf.769.

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6. Killu A. M., Grupper A., Friedman P.A. et al. Predictors and outcomes of’ super-response” to cardiac resynchronization therapy. Journal of cardiac failure. 2014; 20(6): 379.

7. van der Heijden A. C., Höke U., Thijssen J. et al. LongTerm Echocardiographic Outcome in Super-Responders to Cardiac Resynchronization Therapy and the Association With Mortality and Defibrillator Therapy. The American journal of cardiology. 2016; 118(8): 1217.

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9. Cvijic M., Zizek D., Antolic B., Zupan I. Electrocardiographic parameters predict super-response in cardiac resynchronization therapy. Journal of electrocardiology. 2015; 48(4): 593.

10. Ghani A., Delnoy P.P., Smit J.J. et al. Association of apical rocking with super-response to cardiac resynchronisation therapy. Netherlands heart journal: monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation. 2016; 24(1): 39.

11. Tian Y., Zhang P., Li X. et al. True complete left bundle branch block morphology strongly predicts good response to cardiac resynchronization therapy. Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2013; 15(10): 1499.

12. Jackson T., Sohal M., Chen Z. et al. A U-shaped type II contraction pattern in patients with strict left bundle branch block predicts super-response to cardiac resynchronization therapy. Heart rhythm: the official journal of the Heart Rhythm Society. 2014; 11(10): 1790.

13. Guo J.P., Wang Y.T., Shan Z.L. et al. Role of electrocardiogram in predicting cardiac resynchronization therapy response. Zhonghua xin xue guan bing za zhi. 2016; 44(6): 483.

14. Witt C. M., Wu G., Yang D. et al. Outcomes with left bundle branch block and mildly to moderately reduced left ventricular function. JACC: Heart Failure. 2016; 4(11): 897-903.

15. Vereckei A., Szelényi Z., Kutyifa V. et al. Novel electrocardiographic dyssynchrony criteria improve patient selection for cardiac resynchronization therapy. Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2016; doi: 10.1093/europace/euw326.

16. Niels R. Assessment of mechanical dyssynchrony in cardiac resynchronization therapy. Dan Med J. 2014; 61(12): B4981.

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23. Galli E., Leclercq C., Donal E. Mechanical dyssynchrony in heart failure: Still a valid concept for optimizing treatment? Archives of cardiovascular diseases. 2017; 110(1): 60-68.

24. Vukajlovic D., Milasinovic G., Angelkov L. et al. Contractile reserve assessed by dobutamine test identifies super-responders to cardiac resynchronization therapy. Archives of medical science: AMS. 2014; 10(4): 684.

25. Rickard J., Cheng A., Spragg D. Durability of the survival effect of cardiac resynchronization therapy by level of left ventricular functional improvement: fate of “nonresponders”. Heart Rhythm. 2014 Mar; 11(3): 412-6.

26. Cay S., Ozeke O., Ozcan F. et al. Mid-term clinical and echocardiographic evaluation of super responders with and without pacing: the preliminary results of a prospective, randomized, single-centre study. Europace: European pacing, arrhythmias, and cardiac electrophysiology: journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2016; 18(6): 842.

27. Rickard J., Grimm R., Popovich Z. et al. Echocardiographic Predictors of Long Term Survival in Patients Undergoing Cardiac Resynchronization Therapy: What is the Optimal Metric? 2017; doi: 10.1111/jce.13175.

28. Gorcsan J., Sogaard P., Bax J.J. et al. Association of persistent or worsened echocardiographic dyssynchrony with unfavourable clinical outcomes in heart failure patients with narrow QRS width: a subgroup analysis of the EchoCRT trial. European heart journal. 2016; 37(1): 49.

29. Ruschitzka F., Abraham W.T., Singh J.P. et al. Cardiac-resynchronization therapy in heart failure with a narrow QRS complex. New England Journal of Medicine. 2013; 369(15): 1395-1405.

30. Chung E., Leon A., Tavazzi L. et al. Results of the Predictors of Response to CRT (prospect) Trial. Circulation. 2008; 117 (20): 2608-2616.